Tension-Dependent Stability of Torsionally Constrained DNA: Melting Precedes Overwinding
نویسندگان
چکیده
منابع مشابه
Impact of DNA twist accumulation on progressive helical wrapping of torsionally constrained DNA.
DNA wrapping is an important mechanism for chromosomal DNA packaging in cells and viruses. Previous studies of DNA wrapping have been performed mostly on torsionally unconstrained DNA, while in vivo DNA is often under torsional constraint. In this study, we extend a previously proposed theoretical model for wrapping of torsionally unconstrained DNA to a new model including the contribution of D...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2015
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2014.11.1286